Occupational therapy has a distinct role in cancer rehabilitation across the continuum of care. This course will address the growing need for rehabilitation, and specifically occupational therapy services, as part of the standard of care in the early stages of treatment in pediatric central nervous system cancer. This course will also discuss opportunities to advance the profession through advocacy, research, and interdisciplinary and collaborative program development.

About the speaker: Dr. Lauren Stone Kelly OTD, OTR/L

Lauren is currently an Associate Professor of Occupational Therapy and Doctoral Capstone Coordinator at North Central College in Naperville, IL. While she has worked with people across the lifespan, Lauren's primary clinical expertise is with pediatric populations especially children with neurologic, neuro-developmental, and neuro-oncology diagnoses in community and group, inpatient, day rehabilitation and outpatient therapy settings. 

Here are the objectives for my presentation:

1. Understand what deep brain stimulation is and how the system is implanted
2. Be able to identify which patients with Parkinson’s Disease are appropriate for DBS
3. Understand the role of OT in treating patients who have DBS or who may be eligible for DBS
4. Learn how Adaptive DBS can help patients with PD regain more “on-time” with good symptom control
5. Understand expectations for DBS from a therapy perspective

A brief bio:

My name is Colleen and I’m an occupational therapist by background, now working as a clinical specialist at Medtronic in the Deep Brain Stimulation division. I worked for 6 years full time as an OT at 3 different clinical sites, including a SNF, long-term acute care hospital, and outpatient neuro clinic. I specialize in treating neurological conditions and spent most of my full-time years working on a neuro unit which had a Disorders of Consciousness rehabilitation program.  I now work per diem on the weekends at Spaulding Rehab Hospital in Cambridge to maintain my OT skills and continue my passion for helping patients. My current role at Medtronic involves being in the operating room for product/technological support during DBS implantation procedures, providing patients with education on their DBS technology, and assisting physicians with programming the device to control each patient’s unique symptoms while minimizing side effects. 

Current references that are relevant to the presentation/meeting:

- Stanslaski, S., Summers, R.L.S., Tonder, L. et al. Sensing data and methodology from the Adaptive DBS Algorithm for Personalized Therapy in Parkinson’s Disease (ADAPT-PD) clinical trial. npj Parkinsons Dis. 10, 174 (2024). https://doi.org/10.1038/s41531-024-00772-5. Licensed under CC BY 4.0: https://creativecommons.org/licenses/by/4.0/

- Jimenez-Shahed J. Device profile of the percept PC deep brain stimulation system for the treatment of Parkinson’s disease and related disorders. Expert Rev Med Devices. 2021 Apr;18(4):319-332.

- Thenaisie Y, Palmisano C, Canessa A, et al. Towards adaptive deep brain stimulation: clinical and technical notes on a novel commercial device for chronic brain sensing. J Neural Eng. 2021 Aug 31;18(4).

- Yin Z, Zhu G, Zhao B, et al. Local field potentials in Parkinson's disease: A frequency-based review. Neurobiology of Disease. 2021;155:105372’

- Morelli N, Summers RLS. Association of subthalamic beta frequency sub-bands to symptom severity in patients with Parkinson's disease: A systematic review. Parkinsonism & Related Disorders. 2023;110.

- Van Wijk BCM, de Bie RMA, Beudel M. A systematic review of local field potential physiomarkers in Parkinson’s disease: from clinical correlations to adaptive deep brain stimulation algorithms. Journal of Neurology. 2023;270(2):1162-1177.

- Darcy N, Lofredi R, Al-Fatly B, et al. Spectral and spatial distribution of subthalamic beta peak activity in Parkinson's disease patients. Experimental Neurology. 2022:114150.

- Hvingelby, V., Khalil, F., Massey, F., Hoyningen, A., San Xu, S., Candelario-McKeown, J., ... & Krüger, M. T. (2025). Directional deep brain stimulation electrodes in Parkinson’s disease: meta-analysis and systematic review of the literature. Journal of Neurology, Neurosurgery & Psychiatry, 96(2), 188-198